The scientists at, Prince Henry’s Institute, Melbourne, and University of California, have claimed to find a gene in males which controls the primary brain function i.e. physical movement. They say that a male protein, SRY (Sex-Determining Region Y), which was earlier known to shape the testes, produces in the affected brain region in Parkinson’s disease too.
The researchers of Prince Henry’s Institute led by Dr Harley, has invented new tool to find out SRY protein in the brain. UCLA scientists, led by Dr Vilain, did lesser the level of SRY in the substantia nigra in animal models. They discovered a resultant slump in tyrosine hydroxylase, which produces dopamine. That resulted, later, in Parkinson’s disease in men.
Both the teams have concluded that the difference in the SRY gene itself may associated to the inception of Parkinson’s disease. Men with low levels of SRY may be at greater risk of developing the disease.
Men are 1.5 times more probable to develop the disease than women are. This discovery may help to find out the reason why men develop this disease more than women do.
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