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More Effective Treatments for Tuberculosis

The first detailed reports on the biochemistry and structure of a protein-cleaving complex that is essential to the TB bacterium’s survival are published by scientists from the U.S. Department of Energy’s Brookhaven National Laboratory and collaborating institutions. The objective of this publication is to design more effective treatments for tuberculosis (TB).

It is in the March 2006 issue of Molecular Microbiology that features a rendition of the ‘proteasome’ structure on its cover, the research is published in two papers. The papers feature a rendition of the ‘proteasome’ structure on its cover.

Biophysicist Huilin Li, who led Brookhaven’s role in the research said, ‘Understanding the structure and biochemistry of this proteasome, and how it is different from those found in human cells, could greatly improve prospects for developing specific proteasome-based anti-tuberculosis treatments.’

Via: Science Daily

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