Researchers at the University of Rochester Medical Center have come up with an astounding finding that says that inflammation as a result of disease or injury acts as a protector of the brain of patients suffering from Alzheimer. The latest find contradicts the otherwise familiar fact that inflammation from injury adds to the brain’s woes.
The researchers expound, inflammation instead acts as a protector of the brain of Alzheimer’s patients by helping them get rid of clusters of material known as amyloid plaques, constituting peptide amyloid beta, which are a characteristic of the disease. The researchers believe that main role is played by brain cells called microglia, the major immune cell that rushes to injury sites and helps repair and clean up wounds in the brain.
Published in the Journal of Clinical Investigation, the study suggests that doctors should be very careful with molecular events widely considered to be harmful to people suffering from the disease. And care must also be taken of before blocking all inflammatory responses in Alzheimer’s disease. Because this might hamper beneficial processes that are part of the body’s adaptive response to fight plaques.
The new findings are hoped to be helpful as they may replenish efforts to develop a vaccine against Alzheimer’s by engaging the body’s immune system. The probability to treat Alzheimer’s disease by altering the immune system is remarkable. Caution is the keyword for humans because the experiment has been conducted on mice, and more exploration is required in this regard.
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Via:Sawf