Prei-mplantation genetic diagnosis is a screening process to determine any genetic disease or chromosomal disorder in the embryo done prior to embryo transfer. It gives doctors the option to pick the disease-free healthy embryo that would result in healthy babies. Diseases tested with PGD are Cystic fibrosis, Thalassemia, Myotonic Dystropy, Fragile X and Tay Sachs. This also helps in sex determination for couples looking for healthy gender balance in families.
Preimplantation Genetic Screening (PGS) is done for detecting aneuploidy (a condition with additional or missing chromosomes) in embryos that may lead to miscarriage and implantation failure. PGS improves the success rate of pregnancy but it can be an expensive cost addition to IVF treatment. PGS is recommended in cases of severe male infertility or for women aged above 38-39 with previous records of miscarriage. Both PGD and PGS come under the umbrella term PGT or Preimplantation Genetic Testing.